Curriculum Vitae

Education

• Ph.D in Biostatistics, Boston University, 2027 (expected)
• B.A. in Mathematics, Boston College, 2022

Dissertation

• May 2025 - Present (Advisor: Prasad Pratil)
  • Advancing Ensemble Methods: I am interested in model generalization for ensemble learning methods with multi-site data with applications in targeted gene discovery.

Research experience

• June 2022 - Present: Graduate Research Assistant (Research Advisors: Mark Logue and Yorghos Tripodis)
  • Conducted epigenome-wide survival analysis of DNA methylation in relation to Alzheimer’s disease onset using approximately 750,000 Cox proportional hazards models
  • Designed a machine learning pipeline with multimodal clinical and cognitive data to optimize Alzheimer’s disease clinical trial enrollment, boosting trial statistical power by as much as 50%, while enhancing interpretability and equity in patient selection.
  • Built a causal mediation framework linking SNPs, methylation, and PTSD severity using counterfactual modeling
  • Conducted the largest Alzheimer’s GWAS meta-analysis to date, identifying novel loci through integration of multi-cohort summary statistics
• February 2021 - May 2022: Undergraduate Research Assistant
  • Conducted research on probabilistic models for predicting structural changes in social networks
  • Contributed to a publication presenting a streamlined proof of existence and uniqueness of maximum likelihood estimates (MLEs) in exponential random graph models (ERGMs)
  • Supervisor: Kathryn Lindsey

Skills

• Programming: R (tidyverse, dplyr, caret), Python (scikit-learn, pandas, PyTorch), SAS, Bash, SQL
• Machine Learning: Supervised/unsupervised learning, ensemble methods, neural networks
• Statistical Modeling: GLMs, mixed-effects models, survival analysis, causal inference

Publications

Association between PM2.5 air pollution and social deprivation in Western Pennsylvania

Bryan, Luke, Whitman, Ella M, Bayly, Henry, Landrigan, Philip J. Association between PM2.5 air pollution and social deprivation in Western Pennsylvania. Environmental Epidemiology 9(3):p e386, June 2025. | DOI: 10.1097/EE9.0000000000000386

Barriers to recruitment of an observational SARS-CoV-2 emergency department cohort at Boston Medical Center

Thomson, S.J., Mistry, R., Bayly, H. et al. Barriers to recruitment of an observational SARS-CoV-2 emergency department cohort at Boston Medical Center. BMC Emerg Med 25, 68 (2025). https://doi.org/10.1186/s12873-025-01224-w

The Impact of COVID-19 and Socioeconomic Determinants on Appointment Non-Attendance in an Urban Otolaryngology Clinic: A Retrospective Analysis From a Safety Net Hospital

Puyo EM, Salvati LR, Garg N, et al. The Impact of COVID-19 and Socioeconomic Determinants on Appointment Non-Attendance in an Urban Otolaryngology Clinic: A Retrospective Analysis From a Safety Net Hospital. Annals of Otology, Rhinology & Laryngology. 2024;134(2):117-124. doi:10.1177/00034894241295475

Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture

Morey, R.A., Zheng, Y., Bayly, H. et al. Genomic structural equation modeling reveals latent phenotypes in the human cortex with distinct genetic architecture. Transl Psychiatry 14, 451 (2024). https://doi.org/10.1038/s41398-024-03152-y

AI-generated text in otolaryngology publications: a comparative analysis before and after the release of ChatGPT.

Carnino, J.M., Chong, N.Y.K., Bayly, H. et al. AI-generated text in otolaryngology publications: a comparative analysis before and after the release of ChatGPT.. Eur Arch Otorhinolaryngol 281, 6141–6146 (2024). https://doi.org/10.1007/s00405-024-08834-3

Factors influencing hospital charges for tonsillectomy to treat obstructive sleep apnea in children

Carnino, J.M., Mwaura, A.M., Bayly, H. et al. Factors influencing hospital charges for tonsillectomy to treat obstructive sleep apnea in children. Sleep Breath 28, 2205–2211 (2024). https://doi.org/10.1007/s11325-024-03072-7

Appointment Factors Contributing to Children with Speech Disorders Missing Speech and Language Pathology Appointments

Carnino JM, Salvati LR, Bayly H, et al. Appointment Factors Contributing to Children with Speech Disorders Missing Speech and Language Pathology Appointments. Clinical Pediatrics. 2024;63(12):1664-1669. doi:10.1177/00099228241235440

Looking under the lamp-post: quantifying the performance of contact tracing in the United States during the SARS-CoV-2 pandemic

Bayly, H., Stoddard, M., Van Egeren, D. et al. Looking under the lamp-post: quantifying the performance of contact tracing in the United States during the SARS-CoV-2 pandemic. BMC Public Health 24, 595 (2024). https://doi.org/10.1186/s12889-024-18012-z

Exploring the appointment factors affecting pediatric patients with swallow disorders: Implications for speech and language pathology attendance

Carnino JM, Bayly H, et al. Exploring the appointment factors affecting pediatric patients with swallow disorders: Implications for speech and language pathology attendance. International Journal of Pediatric Otorhinolaryngologyh.

Talks

Learning Regional Uncertainty to Calibrate Predictive Models in Clinical Settings

September 03, 2025

Poster at Health Data Science Poster Session, Boston, MA, USA

The Genetic Overlap Between Multisite Chronic Pain and PTSD Severity

June 01, 2025

Poster at Behavioral Genetics Association 55th Annual Meeting, Atlanta, GA

Improving AD Clinical Trial Enrollment Using Machine Learning

May 01, 2025

Talk at Red Rock Data Science Conference, St. George, UT, USA

Connecting the Dots: Overlapping Gene Expression Signatures in Human BNST and PTSD Across Brain Regions and Mouse Models

September 01, 2024

Talk at International Society for Traumatic Studies, Boston, MA, USA

Teaching

Statistical Methods in Epidemiology

Statistical Computing with SAS